A burned child in agony. Application of heparin collagen membrane on a child
in India thermal disaster burned in the thermal disaster by Dr. V. Jayaraman.

• “Heparin improved care, is cost effective, and there is good healing.”
• Consistently found significant benefits similar to Drs. Saliba, Kruggel, and Mangus with use of heparin comparing studies of 30 or 100 burned patients treated with heparin compared to 30 or 100 similar burned patients not treated with heparin.
• Used antibiotics in all patients because of the high temperature and humidity in India. Used diluted solutions of heparin in larger volumes topically.
• Used heparin soaked membranes to cover burn surfaces previously treated with heparin and reapplied them until burns were healed.
• Found and proved that the mechanism for enhanced and shortened healing of burns in the middle granulation phase was heparin effect on collagen fibers in the burn wound in 2 distinct sequential patterns:
  • 1st, heparin significantly accelerated the production and deposition of collagen in the burn wound in the first phase.
  • Then, heparin decelerated production and actually increased the re-absorption of collagen in the 2nd phase, so as to prevent an accumulation of collagen that would be a raised fibrous scar in the healed burn.
• "Use of heparin has enabled us to treated more burned patients. In India, prior to use of heparin, the cost of treating burns of more than 25-30% size was so prohibitively high and unsustainable by the Government, that those patients were given morphine to relieve pain and they died. With use of heparin much larger burns of almost all size are now effectively and affordably treated.”
• As a consequence, the Government of India now supplies and sends heparin-collagen membranes to treat the many burned persons at sites of thermal disasters - for example, the horrendous two railway car explosion-fires on the New Dephi India to Lahore Pakistan train act of terrorism in 2007.
• Attended and presented studies in SBI sponsored eight Int’l Heparin Therapy in Burns Meetings, Conferences, Symposiums, and Congresses usually accompanied by Assistant Prof. of Plastic Surgery Dr. V. Jayaraman MD, Ms., MCh., MNAMs, Dip.NB., PhD. Government Kilpauk Medical College & Hospital, Chennai India.
• Independently and with Dr. V. Jayaraman, presented heparin therapy in burns in Malaysia, Singapore, Bahrain, Kuwait, Australia, Austria, and in cities of Berlin in Germany, Seattle in USA, and Seoul, Korea.
• Responded to Thermal Disaster in Bali Indonesia, but unable to assist local doctors as survivors largely were air evacuated to their homeland in Australia.
• Dr Jayaraman flew to the Kumbakonam Childrens School Thermal Disaster in South Central India and with participation by Dr. Ramakrishnan successfully treated the surviving children with heparin and collagen membranes containing heparin.(See pictures above.)
   

Dr. T.S. Venakatachalapathy MD, Dr. Raghuveer, Fellow college of Surgeons, Plastic Surgeon Mch. And Dr. Mohan S. Kumar, MD, Fellow College of Surgeons, Mch Plastic Surgeon, Chief of Plastic Surgery, and Director of the Burn Center, Pondicherry Indira Gandhi Government General Hospital, Burn Center Department, Pondicherry, India, Started adding heparin administered topically in burned patients in 2004.